Caspar Varlet and his wife, Judith Tentenier, lived in the cities of Cologne, Germany, in Utrecht and Amsterdam, Netherlands, in New Amsterdam (New York), and Hartford, Connecticut. They had a family of twelve children, eight of whom survived to adulthood, all but one of whom emigrated to North America. These children, some of whom married into families well-known in early American history, lived in the Netherlands and in various locations in colonial North America, which after their lifetimes became the states of Virginia, Maryland, New York, New Jersey and Connecticut. We provide information about the ancestors and relatives of the American Varlet family, who lived in the Netherlands, and about various industries in which they were involved.